COORDINATED HIBERNATION OF TRANSCRIPTIONAL AND TRANSLATIONAL APPARATUS DURING GROWTH TRANSITION OF ESCHERICHIA COLI TO STATIONARY PHASE

Coordinated Hibernation of Transcriptional and Translational Apparatus during Growth Transition of Escherichia coli to Stationary Phase

ABSTRACT In the process of Escherichia coli K-12 growth from exponential phase to stationary, marked alteration takes place in the pattern of overall genome expression through modulation of both parts of the transcriptional and translational apparatus.In transcription, the sigma subunit with promoter recognition properties is replaced from the grow

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Newly Identified Deficiencies in the Multiple Sclerosis Central Nervous System and Their Impact on the Remyelination Failure

The pathogenesis of multiple sclerosis (MS) remains enigmatic and controversial.Myelin sheaths in the central nervous system (CNS) insulate axons and allow saltatory nerve conduction.MS brings about the destruction of myelin sheaths and the myelin-producing oligodendrocytes (ODCs).The conundrum of remyelination failure is, therefore, crucial in MS.

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